The Patent Cliff
March 2026 — India's patent wall on Semaglutide collapses. Dr. Reddy's, Zydus, Sun Pharma flood the market. What cost ₹20,000/month is now in your neighbourhood fridge.
FOXO · Life++
The Patent Cliff & the Indian Belly
Newsletter visual assets · May 2026
5 assets · v2
TOFIThin Outside, Fat Inside
The TOFI phenotype. At a normal BMI, high visceral fat wraps your organs. The Indian belly isn't always visible — but it's always dangerous.
BiologyA Peptide Is a Signal
Insulin says: store this energy. GLP-1 says: we're full. Oxytocin says: bond. Before you send new instructions, know what your body is already saying.
FrameworkThe Three Tiers
Endogenous signals your body makes. Regulated medicine with clinical trials. The grey-market wild west. Know which tier you're looking at before making any decision.
FOXOFoundation First
A peptide signal — no matter how high-tech — fails if it lands in a body that hasn't slept, isn't moving, and is drowning in inflammation. Build the base first.